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Quest Diagnostics therapeutic area (TA) datasets are curated, indication-specific sets of clinical and genetic data, extracted from our comprehensive repository of over 70 billion lab results. These deidentified datasets are meticulously designed and tailored to support various objectives across therapy development and provide flexibility across the enterprise. 

Broad coverage

Our deidentified datasets encompass over 50 indications across key therapeutic areas, providing a robust foundation for research, clinical trials, and commercialization.

Data tokenization

Quest data goes through a tokenization process to provide deidentified lab data, ensuring regulatory compliance and improving data privacy for patients.

Enterprise licensing

  • Enable wide access and utilization across various departments including R&D, clinical operations, regulatory, marketing, and saleQ
  • Attain cost savings and operational efficiencies through a consolidated enterprise contract rather than several individual license agreement
  • Continuous availability and scalability to meet changing needs
*Based on internal cost calculations on separate licensing.

  

Start your product's journey to market with Quest

Quest deidentified data can be purchased directly from Quest and overlapped with other internal data sources or purchased through our preferred data partners to reach a desired patient cohort, ensuring minimal disruption to current workflows and processes.


Quest TA datasets provide clear insights

These datasets offer a unique blend of retrospective and prospective data, helping researchers and pharmaceutical companies to gain deep insights and drive the development and successful commercialization of next-generation therapies. 

Test-Based Cohort

Focuses on indication-specific diagnostic tests over the last 5 years, plus 1-year prospective. 
 This dataset is ideal for researchers seeking to study critical biomarkers and treatment responses linked to specific tests. 

Patient-Centric Cohort

Includes all lab encounters for patients who meet the criteria for specific therapeutic areas, offering a complete longitudinal record over the last 5 years, plus 1-year prospective. This deidentified dataset allows for a comprehensive analysis of patient journeys, outcomes, and the identification of comorbidities.


Quest TA datasets address a broad spectrum of conditions

Quest Diagnostics offers comprehensive TA datasets across a wide range of key therapeutic areas, providing researchers and clinicians with invaluable tools to help drive innovation in treatment and care. 
 Our datasets cover over 50 diseases and comprise clinical biomarkers, gene biomarkers, LOINC codes, and ICD codes. 

Datasets available now

Oncology datasets

Indication Clinical tests Genetic biomarkers Diagnosis codes
Breast cancer

50+ related tests, including:

  • Cancer Ag 15-3 in serum or plasma
  • Cancer Ag 27-29 in serum or plasm
  • Carcinoembryonic Ag in serum or plasma

40+ genes, including:

  • BRCA 1 and 2
  • HER 2/ ERBB2
  • PIK3CA
  • PALB2
  • ESR1
  • CHEK2

40+ diagnosis codes, including:

  • C44
  • C50
Colorectal cancer

30+ related tests, including:

  • Carcinoembryonic Ag in serum or plasma
  • Alanine aminotransferase in serum or plasma
  • Aspartate aminotransferase in serum or blood

20+ genes, including:

  • MLH1, MSH2, MSH6
  • PMS2
  • BRAF
  • APC
  • PIK3CA
  • ERBB2
  • KRAS
  • NRAS

20+ diagnosis codes, including:

  • C1J
  • C1H
  • C2T
  • C2F
  • C7A
Non-small cell lung cancer

40+ related tests, including:

  • Platelets in blood by automated count
  • Carcinoembryonic Ag in serum or plasma

30+ genes, including:

  • KRAS
  • ALK
  • EML4
  • BRAF

10+ diagnosis codes, including:

  • C34
Ovarian cancer

40+ related tests, including:

  • Cancer Ag 125 in serum or plasma
  • Human epididymis protein 4 in serum 
 or plasma
  • Alpha-1-fetoprotein in cerebral spinal fluid

15+ genes, including:

  • ERBB2
  • MLH1, MSH2, MSH6
  • BRCA 1/BRCA 2
  • NRAs
  • KRAs
  • RET

4 diagnosis codes, including:

  • C56
Prostate cancer

40+ related tests, including:

  • Prostate-specific Ag in serum or plasma
  • PCA3 score in urine by molecular genetics method
  • PCA3 score in urine; qualitative by molecular genetics method
  • Prostate-specific Ag free in serum or plasma

15+ genes, including:

  • AR
  • HOXB13
  • CHECK2
  • FANCA
  • TP43
  • PALB2
  • ATM

2 diagnosis codes, including:

  • C61
  • R97
Kidney cancer (renal cell carcinoma)

60+ related tests, including:

  • Glomerular filtration rate in serum, plasma or blood by creatinine-based formula
  • Serum creatinine
  • Lactate dehydrogenase in serum or plasma by pyruvate to lactate reaction

30+ genes, including:

  • FH
  • FLCN
  • MET
  • SDHA
  • TSC1, TSC2
  • VHL
  • NTRK 1

4 diagnosis codes, including:

  • C64
  • C7A
Liver cancer (hepatocellular carcinoma)

350+ related tests, including:

  • Alpha-1-fetoprotein tumor marker in serum or plasma
  • Hepatitis B virus surface Ag in serum or blood by immunoassay
  • Hepatitis C virus Ab in serum or plasma by immunoassay

15+ genes, including:

  • TP53
  • RET
  • MLH1, MLH2, MSH6, PSM2
  • AXIN
  • FGF19
  • CD274
  • TERT

5+ diagnosis codes, including:

  • C22
Multiple myeloma

200+ related tests, including:

  • Albumin in serum or plasma
  • Kappa light chains free in serum
  • Lambda light chains in serum or plasma

35+ genes, including:

  • CXCR4
  • MYD88
  • TP53
  • CCND1
  • FGFR3
  • CD38

3 diagnosis codes, including:

  • C90

Gastroenterology datasets

Indication Clinical tests Genetic biomarkers Diagnosis codes
Crohn disease

90+ related tests, including:

  • C-Reactive Protein in serum or plasma
  • Erythrocyte sedimentation rate by Westergren method
  • Calprotectin in stool

5+ genes, including:

  • ATG16L1
  • IL23R
  • FCGR3A
  • NOD2/CARD15

30+ diagnosis codes, including:

  • K50
Ulcerative colitis (UC)

5+ related tests, including:

  • Albumin in serum or plasma
  • Hemoglobin in blood
  • Erythrocyte sedimentation rate by Westergren method
  • C-Reactive Protein in serum or plasma

5+ genes, including:

  • HLA-DRB1
  • IL23R
  • JAK2
  • CARD9
  • HL-DQA1

30+ diagnosis codes, including:

  • K51

Immunology/rheumatology datasets

Indication Clinical tests Genetic biomarkers Diagnosis codes
Rheumatoid arthritis

40+ related tests, including:

  • Rheumatoid factor IgA in serum
  • Rheumatoid factor IgG in serum
  • Rheumatoid factor IgM in serum
  • Cyclic citrullinated peptide IgG Ab in serum or plasma
  • C-Reactive Protein in serum or plasma

10+ genes, including:

  • IL23R
  • JAK2
  • CARD9
  • HLA-DQA1

30+ diagnosis codes, including:

  • M05
  • M06
  • M08

Infectious diseases datasets

Indication Clinical tests Genetic biomarkers Diagnosis codes
HIV

180+ related tests, including:

  • HIV genotype
  • HIV 1 + 2 Ab + HIV1 p24 Ag in serum or plasma by immunoassay
  • HIV 1 RNA in serum or plasma by NAA with probe detection
  • HIV 2 proviral DNA in blood by NAA with probe detection

5+ genes, including:

  • HLAB
  • KIR
  • CCR5
  • UGT1A1
  • ABCB1

1 diagnosis code:

  • B20

 

Datasets coming soon

  • Acute lymphoblastic leukemia
  • Acute myelogenous leukemia
  • Adrenocortical cancer
  • Alzheimer’s disease
  • Appendiceal carcinoma
  • Basal cell carcinoma
  • Bile duct cancer
  • Bladder cancer
  • Brain cancer
  • Cardiomyopathy
  • Celiac disease
  • Cerebrovascular disease
  • Cervical cancer
  • Chlamydia genital infection
  • Chronic kidney disease
  • Chronic lymphocytic leukemia
  • Congenital heart disease
  • Coronary artery disease
  • Cystic nephroma
  • Lymphoma, diffuse large B-cell
  • Endocarditis inflammation
  • Endometrial cancer
  • Follicular lymphoma
  • Friedreich ataxia
  • Gallbladder cancer
  • Gastrointestinal cancer
  • Gastrointestinal stromal tumor
  • Gaucher disease
  • Giant cell arthritis
  • Gout
  • Guillain-barre syndrome
  • Hashimoto
  • Heart failure
  • Hemolytic disease of the fetus and newborn
  • Hereditary paraganglioma-pheochromocytoma syndrome
  • Hodgkin’s lymphoma
  • Hyperkalemia
  • Hyperphosphatemia
  • Hypertensive heart disease
  • Hyperthyroidism
  • Hypothyroidism
  • Idiopathic inflammatory myopathy
  • Leiomyosarcomas
  • Leukemia
  • Lymphoblastic lymphoma
  • Mantle cell lymphoma
  • Meningioma
  • Mesothelioma
  • Myasthenia gravis
  • Neuroendocrine neoplasm
  • Non-alcoholic steatohepatitis
  • Obesity
  • Oropharyngeal cancer
  • Pancreatic cancer
  • Parathyroid cancer
  • Parkinson’s disease
  • Peripheral T-cell lymphoma
  • Pleuropulmonary blastoma
  • Testicular cancer
  • Thyroid cancer
  • Type 1 diabetes
  • Type 2 diabetes
  • Ureter cancer
  • Uterine cancer
  • Peripheral vascular disease
  • Primary hypertension
  • Psoriatic arthritis
  • Pulmonary heart disease
  • Renal artery stenosis
  • Sickle cell
  • Sjögren’s syndrome
  • Systemic lupus erythematosus
  • Thrombotic thrombocytopenic purpura
  • Warm autoimmune hemolytic anemia

To see the full list of biomarkers and tests included in our databases, please fill out the following form:

Please remember that email, including this web form, is not a secure method of communication. Do not submit personal information, including user names and passwords, social security numbers, or personal health information through this form.

To see the full list of biomarkers and tests included in our databases, please fill out the following form:

Please remember that email, including this web form, is not a secure method of communication. Do not submit personal information, including user names and passwords, social security numbers, or personal health information through this form.

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The Quest advantage

Quest Diagnostics offers an unmatched scale and breadth of laboratory data, solidifying our position as the premier source for real-world evidence in therapeutic research.