Coxsackie B (1-6) Antibodies, Serum

The requested test was performed on this specimen; however, the result cannot be reported because of interference from anti-complement activity.

Anti-complement activity is observed when patient serum fixes or destroys complement in the absence of any added test antigen. Such activity leads to inconclusive results in this complement fixation assay. Anti-complement activity may be due to a number of factors such as circulating immune complexes, immunoglobulin aggregation, rheumatoid factors, hemolysis, excessive freezing and thawing of the sample, detergent or microbial contamination in the specimen, and some medications.

Consider ordering test code 15082, Enterovirus RNA, Qualitative Real-Time PCR. This assay is used to detect the presence of enterovirus RNA (including enterovirus, echovirus, Coxsackievirus, and poliovirus).