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Quest Diagnostics

Peripheral neuropathy

A differential diagnosis can help guide optimal therapies

Peripheral neuropathies are diseases or conditions that affect the peripheral nerves, causing numbness, pain, weakness, and cramping. They may be caused by gene mutations, toxin or drug exposure, physical trauma, or inflammation.

The successful identification of immune-mediated syndromes can have a significant impact on a patient’s functionality and quality of life.

Serum autoantibodies can be valuable tools to aid in diagnosis

Because serum autoantibodies are markers for a variety of immune-mediated disorders, they can be valuable in aiding diagnosis and helping physicians treat disorders with optimal, appropriate therapies. Our tests can aid in the differential diagnosis of patients presenting with peripheral neuropathy after common causes have been ruled out.

Testing patients who present with peripheral neuropathies can help:

  • Pursue a definitive diagnosis
  • Identify treatment options
  • Offer appropriate treatment and avoid contraindicated medications

Why order peripheral neuropathy testing from Quest

We offer both genetic and autoimmune peripheral neuropathy testing

Our tests, along with clinical, electrophysiological, and immunological data, can help qualify immune motor neuropathies and other lower motor neuron disorders

Testing that can help distinguish treatable neuropathies

Test name
SensoriMotor Neuropathy Profile with Recombx® -Complete (GALOP, ™ Co-GM1, Co-GD1b, Co-Asialo-GM1, MAG, SGPG, GD1a, Sulfatide, Recombx® Hu) 
Sensory Neuropathy Complete Antibody Panel (Hu, GD1b, GQ1b, MAG, SGPG, MPO, PR3, SS-A, SS-B)
Sulfatide Autoantibody Test
Test codes may vary by location. Please contact your local laboratory for more information. 

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